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Article

The FOXM1/BUB1B signaling pathway is essential for the tumorigenicity and radioresistance of glioblastoma

12 Oct 2017

Abstract excerpt

Accumulating evidence indicates that mitotic checkpoint serine/threonine kinase B (BUB1B) plays a critical role in multiple types of cancer. However, the biological function and molecular regulatory mechanism of BUB1B in glioblastoma (GBM) remain unclear. In the present study, we identified that BUB1B expression was enriched in GBM tumors and was functionally required for tumor proliferation both in vitro and in...

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PMID: 29039578
DOI: 10.3892/or.2017.6032

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