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Article

Glioblastoma Multiforme Formation and EMT: Role of FoxM1 Transcription Factor

3 Feb 2015

Abstract excerpt

Glioblastoma multiforme (GBM) is one of the most malignant cancers in human brain. The prognosis of GBM is extremely poor because it is resistant to radiotherapy and chemotherapy. Improving understanding of the tumor biology brings some new hope to the treatment of GBM. In this review, we discuss the evidence that FoxM1 promotes the development and progression of GBM by regulating key factors involved in cell...

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PMID: 25506897
DOI: 10.2174/1381612821666141211115949

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