Article
The ERAP gene is associated with HCV chronic infection in a Chinese Han population.
Human immunology - 1 Nov 2017
Liu Shuyuan, Cao Danfeng, Shen Yunsong, Li Yalin, Li Ying, Shi Li, Yu Jiankun, Li Chuanyin, Zhang Xinwen, Sun Mingbo, Yao Yufeng
Abstract excerpt
Endoplasmic reticulum aminopeptidases (ERAPs), ERAP1 and ERAP2, are critical components in the antigen-presentation system and are specialized to produce optimal-sized peptides for HLA I binding. ERAP gene polymorphisms have been correlated with HLA-associated diseases. To investigate the association between ERAP gene polymorphisms and HCV chronic infection, a TaqMan assay was used to genotype 4 SNPs (rs27044,...
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