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Article

Identification of novel variants in HLA class II region related to HLA DPB1 expression and disease progression in patients with chronic hepatitis C.

Journal of medical virology - 1 Sept 2017

Hiramatsu Katsushi, Matsuda Hidetaka, Nemoto Tomoyuki, Nosaka Takuto, Saito Yasushi, Naito Tatsushi, Takahashi Kazuto, Ofuji Kazuya, Ohtani Masahiro, Suto Hiroyuki, Yasuda Toshihiro, Hida Yukio, Kimura Hideki, Soya Yoshihiro, Nakamoto Yasunari

Abstract excerpt

Recent genome-wide studies have demonstrated that HLA class II gene may play an important role in viral hepatitis. We studied genetic polymorphism and RNA expression of HLA class II genes in HCV-related liver diseases. The study was performed in groups consisting of 24 patients with HCV-related liver disease (12 of persistent normal ALT: PNALT group and 12 of advanced liver disease: ALD group) and 26 patients...

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Case-Control Studies
Disease Progression
Gene Expression Profiling
Hepatitis C, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DP beta-Chains

Leukocytes, Mononuclear

Real-Time Polymerase Chain Reaction

Sequence Analysis, DNA

Source

Identifiers

PMID: 28332201
DOI: 10.1002/jmv.24814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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