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Article

LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers.

Gynecologic oncology - 1 Dec 2017

Xia Zhouchunyang, Cochrane Dawn R, Anglesio Michael S, Wang Yi Kan, Nazeran Tayyebeh, Tessier-Cloutier Basile, McConechy Melissa K, Senz Janine, Lum Amy, Bashashati Ali, Shah Sohrab P, Huntsman David G

Abstract excerpt

OBJECTIVE: Endometrioid (ENOC) and clear cell ovarian carcinoma (CCOC) share a common precursor lesion, endometriosis, hence the designation endometriosis associated ovarian cancers (EAOC). Long interspersed nuclear element 1 (LINE-1 or L1), is a family of mobile genetic elements activated in many cancers capable of moving neighboring DNA through 3' transductions. Here we investigated the involvement of specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

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Share to Ovarian Neoplasms

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Source

Identifiers

PMID: 29032825
DOI: 10.1016/j.ygyno.2017.09.032

Genes

CTNNB1
KRAS
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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