Article
Association of interleukin-6-572G/C gene polymorphisms in the Cantonese population with intracranial aneurysms.
Journal of the neurological sciences - 15 Jul 2011
Zhang Guozhong, Tu Yanyang, Feng Wenfeng, Huang Lijin, Li Mingzhou, Qi Songtao
Abstract excerpt
Recent studies have demonstrated that cytokines play an important role in the pathogenesis of intracranial aneurysms (IAs). Interleukin-6 (IL-6) is an important proinflammatory cytokine. In our study, we investigated the association of genetic variants within the gene encoding interleukin-6-572G/C (IL-6-572G/C) with IAs in the Cantonese population. The IL-6-572G/C gene polymorphisms in 182 IA cases and 182...
Topics
- Adult
- Aged
- Asian People
- China
- Female
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Genotype
- Humans
- Interleukin-6
- Intracranial Aneurysm
