Article
Pharmacokinetics and Pharmacodynamics of Meloxicam in East Asian Populations: The Role of Ethnicity on Drug Response.
CPT: pharmacometrics & systems pharmacology - 1 Dec 2017
Aoyama Takahiko, Ishida Yoshimasa, Kaneko Masato, Miyamoto Aoi, Saito Yoshiro, Tohkin Masahiro, Kawai Shinichi, Matsumoto Yoshiaki
Abstract excerpt
We aimed to reanalyze the differences in the pharmacokinetics (PKs) of meloxicam in East Asian populations based on a population approach using previously published data and to investigate the factors found in population PK analysis that affect the pharmacodynamics (PDs) of meloxicam. Population PK analysis was performed in 119 healthy male subjects (30 Japanese, 30 Chinese, 29 Korean, and 30 white) under...
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