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Article

Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.

Journal of clinical pharmacology - 1 Oct 2004

Kim Kiman, Johnson Julie A, Derendorf Hartmut

Abstract excerpt

Interethnic variability in pharmacokinetics can cause unexpected outcomes such as therapeutic failure, adverse effects, and toxicity in subjects of different ethnic origin undergoing medical treatment. It is important to realize that both genetic and environmental factors can lead to these differences among ethnic groups. The International Conference on Harmonization (ICH) published a guidance to facilitate the...

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Identifiers

PMID: 15342610
DOI: 10.1177/0091270004268128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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