Article
Effect of CYP2C9*3 mutant variants on meloxicam pharmacokinetics in a healthy Chinese population.
Genetics and molecular research : GMR - 13 Feb 2014
Zhang M, Yang Y, Zhao G, Di X, Xu L, Jiang N, Xu J, Xu X
Abstract excerpt
The aim of this study was to investigate the effect of the CYP2C9*3 (CYP2C9 1075 A>C) polymorphism on meloxicam pharmacokinetics in a Chinese population. Twenty-four healthy volunteers were enrolled in this study. The pyrosequencing technique was used to identify polymorphisms of CYP2C9. The concentration of meloxicam in plasma was determined by a high-performance liquid chromatography assay with mass...
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