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Article

Population pharmacokinetics and pharmacogenetics of alcohol in Chinese and Indians in Singapore.

Journal of clinical pharmacy and therapeutics - 1 Apr 2013

Seng K Y, Limenta L M G, Heng D, Lee E J D

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: Interindividual variability in alcohol pharmacokinetics is influenced by a number of factors, including polymorphisms in genes mediating alcohol pharmacology, ethnicity, sex and body size. Several studies have evaluated the population pharmacokinetics of alcohol from breath alcohol measures. None of these studies, however, have evaluated ethnicity and alcohol-metabolizing enzyme...

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Source

Identifiers

PMID: 23240771
DOI: 10.1111/jcpt.12003

Genes

ALDH2

Provenance

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