Article
Possible interethnic differences in omeprazole pharmacokinetics : comparison of Jordanian Arabs with other populations.
Clinical pharmacokinetics - 1 Jan 2006
Shilbayeh Sireen, Tutunji Maha F
Abstract excerpt
BACKGROUND AND OBJECTIVE: Considerable ethnic differences have been reported in the incidence of the poor metaboliser (PM) genotype of cytochrome P450 (CYP) 2C19. The frequency of this genotype was found to be much higher in Oriental persons (13-23%) than in American or European populations (3-5%). There are, however, no valid data published for Arabic subjects. The present study was conducted to evaluate...
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