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Article

Ethnic differences in drug metabolism and toxicity from chemotherapy.

Expert opinion on drug metabolism & toxicology - 1 Mar 2009

Phan Viet Hong, Moore Melissa M, McLachlan Andrew J, Piquette-Miller Micheline, Xu Hongmei, Clarke Stephen J

Abstract excerpt

There is wide inter-individual variability in the pharmacokinetics, pharmacodynamics and tolerance of anticancer drugs. Recent evidence suggests that there is even greater variability between individuals of different ethnicity. Allelic variants of genes encoding drug metabolising enzymes are expressed with different incidences in different ethnic groups, particularly between Asian and Caucasians, and some of...

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Identifiers

PMID: 19331590
DOI: 10.1517/17425250902800153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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