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Article

Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells.

American journal of physiology. Cell physiology - 1 Oct 2017

Al-Ahmad Abraham J

Abstract excerpt

Glucose constitutes a major source of energy of mammalian brains. Glucose uptake at the blood-brain barrier (BBB) occurs through a facilitated glucose transport, through glucose transporter 1 (GLUT1), although other isoforms have been described at the BBB. Mutations in GLUT1 are associated with the GLUT1 deficiency syndrome, yet none of the current in vitro models of the human BBB maybe suited for modeling such a...

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Identifiers

PMID: 28993322
DOI: 10.1152/ajpcell.00116.2017
PMCID: PMC5668574

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