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Article

Mfd translocase is necessary and sufficient for transcription-coupled repair in Escherichia coli.

The Journal of biological chemistry - 10 Nov 2017

Adebali Ogun, Sancar Aziz, Selby Christopher P

Abstract excerpt

Nucleotide excision repair in Escherichia coli is stimulated by transcription, specifically in the transcribed strand. Previously, it was shown that this transcription-coupled repair (TCR) is mediated by the Mfd translocase. Recently, it was proposed that in fact the majority of TCR in E. coli is catalyzed by a second pathway ("backtracking-mediated TCR") that is dependent on the UvrD helicase and the guanosine...

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Identifiers

PMID: 28986449
DOI: 10.1074/jbc.C117.818807
PMCID: PMC5682952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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