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Article

A DNA translocation motif in the bacterial transcription--repair coupling factor, Mfd.

Nucleic acids research - 15 Nov 2003

Chambers A L, Smith A J, Savery N J

Abstract excerpt

The bacterial transcription-repair coupling factor, Mfd, is a superfamily II helicase that releases transcription elongation complexes stalled by DNA damage or other obstacles. Transcription complex displacement is an ATP-dependent reaction that is thought to involve DNA translocation without the strand separation associated with classical helicase activity. We have identified single amino acid substitutions...

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Identifiers

PMID: 14602898
DOI: 10.1093/nar/gkg868
PMCID: PMC275562

Genes

TRG

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A DNA translocation motif in the bacterial transcription--repair coupling factor, Mfd.PMID 14602898Read ↗

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