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Article

Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America - 31 Aug 2010

Cohen Susan E, Lewis Cindi A, Mooney Rachel A, Kohanski Michael A, Collins James J, Landick Robert, Walker Graham C

Abstract excerpt

We report observations suggesting that the transcription elongation factor NusA promotes a previously unrecognized class of transcription-coupled repair (TCR) in addition to its previously proposed role in recruiting translesion synthesis (TLS) DNA polymerases to gaps encountered during transcription. Earlier, we reported that NusA physically and genetically interacts with the TLS DNA polymerase DinB (DNA pol...

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Identifiers

PMID: 20696893
DOI: 10.1073/pnas.1005203107
PMCID: PMC2932615

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