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Article

Analysis of clinically relevant somatic mutations in high-risk head and neck cutaneous squamous cell carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2018

Zilberg Catherine, Lee Matthew Weicai, Yu Bing, Ashford Bruce, Kraitsek Spiridoula, Ranson Marie, Shannon Kerwin, Cowley Mark, Iyer N Gopalakrishna, Palme Carsten E, Ch'ng Sydney, Low Tsu-Hui Hubert, O'Toole Sandra, Clark Jonathan R, Gupta Ruta

Abstract excerpt

Cutaneous squamous cell carcinoma is the second most prevalent malignancy, most frequently occurring in the head and neck (head and neck cutaneous squamous cell carcinoma). Treatment of locally advanced or metastatic disease is associated with functional morbidity and disfigurement. Underlying genetic mechanisms are poorly understood. Targeted sequencing of 48 clinically relevant genes was performed on DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits, Gq-G11

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Share to Squamous Cell Carcinoma of Head and Neck

Source

Identifiers

PMID: 28984303
DOI: 10.1038/modpathol.2017.128

Genes

FGFR2
NOTCH1
ABL1
APC
ATM
EGFR
ERBB4
GNAQ
KIT
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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