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Article

AZI23'UTR Is a New SLC6A3 Downregulator Associated with an Epistatic Protection Against Substance Use Disorders.

Molecular neurobiology - 1 Jul 2018

Liu Kefu, Yu Jinlong, Zhao Juan, Zhou Yanhong, Xiong Nian, Xu Jie, Wang Tao, Bell Richard L, Qing Hong, Lin Zhicheng

Abstract excerpt

Regulated activity of SLC6A3, which encodes the human dopamine transporter (DAT), contributes to diseases such as substance abuse disorders (SUDs); however, the exact transcription mechanism remains poorly understood. Here, we used a common genetic variant of the gene, intron 1 DNP1B sequence, as bait to screen and clone a new transcriptional activity, AZI23'UTR, for SLC6A3. AZI23'UTR is a 3' untranslated region...

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Share to 3' Untranslated Regions
Share to Adaptor Proteins, Signal Transducing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Dopamine Plasma Membrane Transport Proteins

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Source

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Identifiers

PMID: 28983843
DOI: 10.1007/s12035-017-0781-2
PMCID: PMC5886844

Genes

AZI2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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