Article
A 40-bp VNTR polymorphism in the 3'-untranslated region of DAT1/SLC6A3 is associated with ADHD but not with alcoholism.
Behavioral and brain functions : BBF - 11 Jun 2015
Šerý Omar, Paclt Ivo, Drtílková Ivana, Theiner Pavel, Kopečková Marta, Zvolský Petr, Balcar Vladimir J
Abstract excerpt
BACKGROUND: ADHD and alcoholism are psychiatric diseases with pathophysiology related to dopamine system. DAT1 belongs to the SLC6 family of transporters and is involved in the regulation of extracellular dopamine levels. A 40 bp variable number tandem repeat (VNTR) polymorphism in the 3'-untranslated region of DAT1/SLC6A3 gene was previously reported to be associated with various phenotypes involving disturbed...
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