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Article

Differential repression by freud-1/CC2D1A at a polymorphic site in the dopamine-D2 receptor gene.

The Journal of biological chemistry - 20 Jul 2007

Rogaeva Anastasia, Ou Xiao-Ming, Jafar-Nejad Hamed, Lemonde Sylvie, Albert Paul R

Abstract excerpt

Freud-1/CC2D1A is a transcriptional repressor of the serotonin-1A receptor gene and was recently genetically linked to non-syndromic mental retardation. To identify new Freud-1 gene targets, data base mining for Freud-1 recognition sequences was done. A highly homologous intronic element (D2-DRE) was identified in the human dopamine-D2 receptor (DRD2) gene, and the role of Freud-1 in regulating the gene at this...

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Source

Identifiers

PMID: 17535813
DOI: 10.1074/jbc.M610038200

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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