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Article

Connexin45 regulates endothelial-induced mesenchymal cell differentiation toward a mural cell phenotype.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2013

Fang Jennifer S, Dai Cuiping, Kurjiaka David T, Burt Janis M, Hirschi Karen K

Abstract excerpt

OBJECTIVE: The focus of this study was to investigate the role of connexin (Cx) 45 in endothelial-induced mural cell differentiation. METHODS AND RESULTS: We created mural cell precursors that stably express only Cx45 in Cx43-deficient mesenchymal cells (ReCx45), and used our in vitro model of blood vessel assembly to assess the capacity of this Cx to support endothelial-induced mural cell differentiation....

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Identifiers

PMID: 23220276
DOI: 10.1161/ATVBAHA.112.255950
PMCID: PMC3737426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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