Article
Significant association of Interleukin-10 genotypes and oral cancer susceptibility in Taiwan.
Anticancer research - 1 Jul 2014
Tsai Chia-Wen, Chang Wen-Shin, Lin Kuo-Cheng, Shih Liang-Chun, Tsai Ming-Hsui, Hsiao Chieh-Lun, Yang Mei-Due, Lin Cheng-Chieh, Bau Da-Tian
Abstract excerpt
Interleukin-10 (IL10) is an immunosuppressive cytokine which may facilitate carcinogenesis by down-regulating interferon-gamma production and supporting tumor escape from the immune response. Polymorphisms within the promoter of IL10 gene may not only contribute to differential IL10 expression levels among individuals but also to oral cancer susceptibility. In this hospital-based study, the association of IL10...
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