Article
Case-control association testing in the presence of unknown relationships.
Genetic epidemiology - 1 Dec 2009
Choi Yoonha, Wijsman Ellen M, Weir Bruce S
Abstract excerpt
Genome-wide association studies result in inflated false-positive results when unrecognized cryptic relatedness exists. A number of methods have been proposed for testing association between markers and disease with a correction for known pedigree-based relationships. However, in most case-contro...
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