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Article

In Vitro Approach To Identify Key Amino Acids in Low Susceptibility of Rabbit Prion Protein to Misfolding.

Journal of virology - 15 Dec 2017

Eraña Hasier, Fernández-Borges Natalia, Elezgarai Saioa R, Harrathi Chafik, Charco Jorge M, Chianini Francesca, Dagleish Mark P, Ortega Gabriel, Millet Óscar, Castilla Joaquín

Abstract excerpt

Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of rare progressive neurodegenerative disorders caused by an abnormally folded prion protein (PrPSc). This is capable of transforming the normal cellular prion protein (PrPC) into new infectious PrPSc Interspecies prion transmissibility studies performed by experimental challenge and the outbreak of bovine spongiform encephalopathy...

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Source

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Identifiers

PMID: 28978705
DOI: 10.1128/JVI.01543-17
PMCID: PMC5709604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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