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Article

Interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach.

Diabetes - 1 Jun 2009

Perry John R B, McCarthy Mark I, Hattersley Andrew T, Zeggini Eleftheria, Weedon Michael N, Frayling Timothy M

Abstract excerpt

OBJECTIVE: Recent genome-wide association studies have resulted in a dramatic increase in our knowledge of the genetic loci involved in type 2 diabetes. In a complementary approach to these single-marker studies, we attempted to identify biological pathways associated with type 2 diabetes. This approach could allow us to identify additional risk loci. RESEARCH DESIGN AND METHODS: We used individual level genotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19252133
DOI: 10.2337/db08-1378
PMCID: PMC2682674

Genes

CCND2
PRICKLE1
SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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