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Article

A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations.

PLoS genetics - 1 Jun 2016

Zhang Han, Wheeler William, Hyland Paula L, Yang Yifan, Shi Jianxin, Chatterjee Nilanjan, Yu Kai

Abstract excerpt

Meta-analysis of multiple genome-wide association studies (GWAS) has become an effective approach for detecting single nucleotide polymorphism (SNP) associations with complex traits. However, it is difficult to integrate the readily accessible SNP-level summary statistics from a meta-analysis into more powerful multi-marker testing procedures, which generally require individual-level genetic data. We developed a...

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Source

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Identifiers

PMID: 27362418
DOI: 10.1371/journal.pgen.1006122
PMCID: PMC4928884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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