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Article

From SNPs to pathways: Biological interpretation of type 2 diabetes (T2DM) genome wide association study (GWAS) results.

PloS one - 1 Jan 2018

Cirillo Elisa, Kutmon Martina, Gonzalez Hernandez Manuel, Hooimeijer Tom, Adriaens Michiel E, Eijssen Lars M T, Parnell Laurence D, Coort Susan L, Evelo Chris T

Abstract excerpt

Genome-wide association studies (GWAS) have become a common method for discovery of gene-disease relationships, in particular for complex diseases like Type 2 Diabetes Mellitus (T2DM). The experience with GWAS analysis has revealed that the genetic risk for complex diseases involves cumulative, small effects of many genes and only some genes with a moderate effect. In order to explore the complexity of the...

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Share to Diabetes Mellitus, Type 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 29617380
DOI: 10.1371/journal.pone.0193515
PMCID: PMC5884486

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APOB
LPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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