Article
A SNP uncoupling Mina expression from the TGFβ signaling pathway.
Immunity, inflammation and disease - 1 Mar 2018
Lian Shang L, Mihi Belgacem, Koyanagi Madoka, Nakayama Toshinori, Bix Mark
Abstract excerpt
INTRODUCTION: Mina is a JmjC family 2-oxoglutarate oxygenase with pleiotropic roles in cell proliferation, cancer, T cell differentiation, pulmonary inflammation, and intestinal parasite expulsion. Although Mina expression varies according to cell-type, developmental stage and activation state, its transcriptional regulation is poorly understood. Across inbred mouse strains, Mina protein level exhibits a bimodal...
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