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Article

High Levels of Circulating Type II Collagen Degradation Marker (CTx-II) Are Associated with Specific VDR Polymorphisms in Patients with Adult Vertebral Osteochondrosis.

International journal of molecular sciences - 29 Sept 2017

Cauci Sabina, Viganò Marco, de Girolamo Laura, De Luca Paola, Perucca Orfei Carlotta, Banfi Giuseppe, Lombardi Giovanni, Brayda-Bruno Marco, Colombini Alessandra

Abstract excerpt

Both vitamin D and collagen have roles in osteocartilaginous homeostasis. We evaluated the association between the circulating 25-hydroxyvitamin D (25(OH)D) type I and II collagen degradation products (CTx-I, and CTx-II), and four vitamin D receptor gene (VDR) polymorphisms, in Italian males affected by low back pain (LBP) due to herniation/discopathy and/or vertebral osteochondrosis. FokI, BsmI, ApaI, and TaqI...

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Share to Collagen Type II
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptide Fragments

Share to Polymorphism, Genetic

Share to Proteolysis

Share to Receptors, Calcitriol

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Source

Open in PubMed Open full text

Identifiers

PMID: 28961166
DOI: 10.3390/ijms18102073
PMCID: PMC5666755

Genes

VDR
LBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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