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Article

FokI polymorphism in the vitamin D receptor gene (VDR) and its association with lumbar spine pathologies in the Italian population: a case-control study.

PloS one - 1 Jan 2014

Colombini Alessandra, Brayda-Bruno Marco, Lombardi Giovanni, Croiset Samantha Jennifer, Vrech Valentina, Maione Vincenzo, Banfi Giuseppe, Cauci Sabina

Abstract excerpt

Alterations in vitamin D homeostasis, mainly involving its nuclear receptor (VDR), could have a role in the pathophysiology of the spine. The association between VDR polymorphisms and spine disorders has been analyzed in different ethnic groups, focusing on the functional FokI polymorphism. However, so far, inconsistent findings were reported. The aims of this study were to evaluate, in the Italian white...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24810167
DOI: 10.1371/journal.pone.0097027
PMCID: PMC4014587

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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