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Vitamin D Receptor gene polymorphisms and plasma levels are associated with lumbar disc degeneration

24 May 2019

Abstract excerpt

The purpose of this study was to investigate the association of Vitamin D Receptor (VDR) gene polymorphisms and VDR levels with lumbar disc degeneration (LDD). TaqMan SNP Genotyping Assay was utilized to probe VDR gene polymorphisms including the FokI (rs2228570), ApaI (rs7975232) and TaqI (rs731236) in 454 patients with LDD and 485 controls. Enzyme-Linked Immunosorbent Assay (ELISA) was used to detect plasma VDR...

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PMID: 31127184
DOI: 10.1038/s41598-019-44373-2

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