Article
Gender differences in the VDR-FokI polymorphism and conventional non-genetic risk factors in association with lumbar spine pathologies in an Italian case-control study.
International journal of molecular sciences - 9 Feb 2015
Colombini Alessandra, Brayda-Bruno Marco, Ferino Lucia, Lombardi Giovanni, Maione Vincenzo, Banfi Giuseppe, Cauci Sabina
Abstract excerpt
Recently, the FokI polymorphism (rs2228570) in the vitamin D receptor gene (VDR) and conventional risk factors were associated with spine disorders in the Italian population, but without gender analysis. Two-hundred and sixty-seven patients (149 males, 118 females) with lumbar spine disorders were assessed by magnetic resonance imaging (MRI) and 254 (127 males, 127 females) asymptomatic controls were enrolled....
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