Article
Pan-cancer analysis reveals presence of pronounced DNA methylation drift in CpG island methylator phenotype clusters.
Epigenomics - 1 Nov 2017
Karpinski Pawel, Pesz Karolina, Sasiadek Maria M
Abstract excerpt
AIM: To provide characteristics of major genomic correlates in CpG island methylator phenotype-high (CIMP-H) subgroups in relation to corresponding non-CIMP-H subgroups by use of phenotypic, DNA methylation and RNAseq data. MATERIALS & METHODS: Twenty-three datasets generated by The Cancer Genome Atlas project encompassing over 7200 unique samples were analyzed. We identified 23 CIMP-H clusters by use of...
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