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Article

BRAF mutation as a potential marker to identify the proximal colon serrated polyps with malignant potential.

International journal of clinical and experimental pathology - 1 Jan 2014

Fu Xiangsheng, Zhang Xiaoyan

Abstract excerpt

A large number of serrated polyps with malignant potential in the proximal colon were underestimated using currently available criteria mostly based on architectural and cytological features, contributing to proximal interval colorectal cancers. Recently, increasing evidences indicate that BRAF((V600E)) mutation is a specific molecular feature and driver of the serrated pathway, and proximal serrated polyps with...

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Source

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Identifiers

PMID: 25550768
PMCID: PMC4270613

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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