Article
Polymorphisms in interleukin 17A gene and coal workers' pneumoconiosis risk in a Chinese population.
BMC pulmonary medicine - 30 Jul 2015
Han Ruhui, Ji Xiaoming, Wu Baiqun, Wang Ting, Han Lei, Yang Jingjin, Zhu Baoli, Ni Chunhui
Abstract excerpt
BACKGROUND: The interleukin 17A (IL-17A) which is located on chromosome 6p and has been linked to chronic inflammation, is an important candidate gene conferring coal workers' pneumoconiosis (CWP). The purpose of this study was to investigate the genetic association between single nucleotide polymorphisms (SNPs) of IL-17A and CWP in a Chinese population. METHODS: We conducted a case-control study to investigate...
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