Article
Sexual Dimorphism, Age, and Fat Mass Are Key Phenotypic Drivers of Proteomic Signatures.
Journal of proteome research - 3 Nov 2017
Curran Aoife M, Fogarty Draper Colleen, Scott-Boyer Marie-Pier, Valsesia Armand, Roche Helen M, Ryan Miriam F, Gibney Michael J, Kutmon Martina, Evelo Chris T, Coort Susan L, Astrup Arne, Saris Wim H, Brennan Lorraine, Kaput Jim
Abstract excerpt
Validated protein biomarkers are needed for assessing health trajectories, predicting and subclassifying disease, and optimizing diagnostic and therapeutic clinical decision-making. The sensitivity, specificity, accuracy, and precision of single or combinations of protein biomarkers may be altered by differences in physiological states limiting the ability to translate research results to clinically useful...
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