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Article

Ubiquitin recognition of BAP1: understanding its enzymatic function.

Bioscience reports - 31 Oct 2017

Hanpude Pranita, Bhattacharya Sushmita, Kumar Singh Abhishek, Kanti Maiti Tushar

Abstract excerpt

BRCA1-associated protein 1 (BAP1) is a nuclear localizing UCH, having tumor suppressor activity and is widely involved in many crucial cellular processes. BAP1 has garnered attention for its links with cancer, however, the molecular mechanism in the regulation of cancer by BAP1 has not been established. Amongst the four UCHs, only BAP1 and UCHL5 are able to hydrolyze small and large ubiquitin adducts but UCHL5...

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Source

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Identifiers

PMID: 28935764
DOI: 10.1042/BSR20171099
PMCID: PMC5665613

Genes

BAP1
UCHL5
BRCA1
UCHL1
UCHL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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