Article
Reversal of chemosensitivity and induction of cell malignancy of a non-malignant prostate cancer cell line upon extracellular vesicle exposure.
Molecular cancer - 8 Oct 2013
Panagopoulos Kiriaki, Cross-Knorr Sam, Dillard Christen, Pantazatos Dionysios, Del Tatto Michael, Mills David, Goldstein Lisa, Renzulli Joseph, Quesenberry Peter, Chatterjee Devasis
Abstract excerpt
BACKGROUND: Extracellular vesicle (EV) trafficking is a fundamental cellular process that occurs in cells and is required for different aspects of pathophysiology. EV trafficking leads to changes in cellular function including apoptosis, angiogenesis and proliferation required for increased tumor formation. RESULTS: We report several phenotypic changes mediated by EVs isolated from non-malignant and malignant...
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