Article

Proteomic profiling of extracellular vesicles distinguishes prostate cancer molecular subtypes

2025-08-02

Abstract excerpt

Prostate cancer is the most common non-cutaneous cancer among men in the United States. Most prostate cancers are driven by androgen receptor (AR) signaling, but there are an increasing number of cases that lose AR and gain neuroendocrine (NE) features (AR−/NE+) or lack both (AR−/NE−). These latter subtypes are particularly aggressive and lethal. Extracellular vesicles (EVs) have shown great potential as biomarker...

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Literature Corpus work: c84d6b7f-3adb-5698-8aba-611be20c4884
DOI: 10.1101/2025.07.31.667906

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