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Exosomal miR‐222‐3p contributes to castration‐resistant prostate cancer by activating mTOR signaling

6 Sept 2023

Abstract excerpt

Despite the clinical benefits of androgen deprivation therapy, most patients with advanced androgen-dependent prostate cancer (ADPC) eventually relapse and progress to lethal androgen-independent prostate cancer (AIPC), also termed castration-resistant prostate cancer (CRPC). MiRNAs can be packaged into exosomes (Exos) and shuttled between cells. However, the roles and mechanisms of exosomal miRNAs involved in...

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PMID: 37671589
DOI: 10.1111/cas.15948

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