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Article

acn-1, a C. elegans homologue of ACE, genetically interacts with the let-7 microRNA and other heterochronic genes.

Cell cycle (Georgetown, Tex.) - 2 Oct 2017

Metheetrairut Chanatip, Ahuja Yuri, Slack Frank J

Abstract excerpt

The heterochronic pathway in C. elegans controls the relative timing of cell fate decisions during post-embryonic development. It includes a network of microRNAs (miRNAs), such as let-7, and protein-coding genes, such as the stemness factors, LIN-28 and LIN-41. Here we identified the acn-1 gene, a homologue of mammalian angiotensin-converting enzyme (ACE), as a new suppressor of the stem cell developmental...

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Identifiers

PMID: 28933985
DOI: 10.1080/15384101.2017.1344798
PMCID: PMC5628652

Genes

ACE
APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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