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Article

Dexamethasone Attenuates the Enhanced Rewarding Effects of Cocaine Following Experimental Traumatic Brain Injury.

Cell transplantation - 1 Jul 2017

Merkel Steven F, Andrews Allison M, Lutton Evan M, Razmpour Roshanak, Cannella Lee Anne, Ramirez Servio H

Abstract excerpt

Clinical studies have identified traumatic brain injury (TBI) as a risk factor for the development of cocaine dependence. This claim is supported by our recent preclinical studies showing enhancement of the rewarding effects of cocaine in mice sustaining moderate controlled cortical impact (CCI) injury during adolescence. Here we test the efficacy of dexamethasone, an anti-inflammatory corticosteroid, to...

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Source

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Identifiers

PMID: 28933216
DOI: 10.1177/0963689717714341
PMCID: PMC5447499

Genes

CCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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