Article
Glucocorticoid receptors in dopaminoceptive neurons, key for cocaine, are dispensable for molecular and behavioral morphine responses.
Biological psychiatry - 1 Aug 2010
Barik Jacques, Parnaudeau Sébastien, Saint Amaux Aurélie Lampin, Guiard Bruno P, Golib Dzib Jose Felipe, Bocquet Olivier, Bailly Alain, Benecke Arndt, Tronche François
Abstract excerpt
BACKGROUND: Psychostimulants and opiates trigger similar enduring neuroadaptations within the reward circuitry thought to underlie addiction. Transcription factors are key to mediating these enduring behavioral alterations. The facilitation of these maladaptive changes by glucocorticoid hormones...
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