Article
Interleukin-10 Deficiency Impairs Reparative Properties of Bone Marrow-Derived Endothelial Progenitor Cell Exosomes.
Tissue engineering. Part A - 1 Nov 2017
Yue Yujia, Garikipati Venkata Naga Srikanth, Verma Suresh Kumar, Goukassian David A, Kishore Raj
Abstract excerpt
Endothelial progenitor cell (EPC)-based therapy has immense potential to promote cardiac neovascularization and attenuate ischemic injury. Functional benefits of EPCs and other adult stem cell therapies largely involve paracrine mechanisms and exosomes secreted by stem cells are emerging as pivotal paracrine entity of stem/progenitor cells. However, modest outcomes after EPC-/stem cell-based clinical trials...
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