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Article

Genetic Variant Near PLXDC2 Influences the Risk of Primary Open-angle Glaucoma by Increasing Intraocular Pressure in the Japanese Population.

Journal of glaucoma - 1 Nov 2017

Mabuchi Fumihiko, Mabuchi Nakako, Takamoto Mitsuko, Sakurada Yoichi, Yoneyama Seigo, Kashiwagi Kenji, Iijima Hiroyuki, Yamagata Zentaro, Aihara Makoto, Iwata Takeshi, Araie Makoto

Abstract excerpt

PURPOSE: The purpose of this study is to assess the association between the genetic variants that were previously reported to be associated with primary open-angle glaucoma (POAG) in the Japanese population and the phenotypic features. METHODS: A total of 661 Japanese patients including 417 patients with POAG [normal tension glaucoma (NTG), n=210; high tension glaucoma (HTG), n=207] and 244 control subjects...

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Source

Identifiers

PMID: 28930887
DOI: 10.1097/IJG.0000000000000790

Genes

PLXDC2
TMTC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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