Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association analysis of variants rs35934224 in TXNRD2 and rs6478746 in LMX1B in primary angle-closure and pseudoexfoliation glaucoma.

European journal of ophthalmology - 1 Jul 2022

Kondkar Altaf A, Sultan Tahira, Alobaidan Abdullah S, Azad Taif A, Osman Essam A, Almobarak Faisal A, Lobo Glenn P, Al-Obeidan Saleh A

Abstract excerpt

OBJECTIVE: Previous genome-wide studies have demonstrated significant pathogenic association between variants rs35934224 within TXNRD2 and rs6478746 near LMX1B in primary open-angle glaucoma. We investigated the association between these variants in primary angle-closure glaucoma (PACG) and pseudoexfoliation glaucoma (PXG) patients of Saudi origin. METHODS: In a case-control study, DNA samples from 249 controls...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies
Share to Exfoliation Syndrome
Share to Genetic Predisposition to Disease
Share to Glaucoma, Angle-Closure
Share to Glaucoma, Open-Angle
Share to Intraocular Pressure
Share to LIM-Homeodomain Proteins
Share to Transcription Factors

Source

Identifiers

PMID: 34461764
DOI: 10.1177/11206721211042547

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association analysis of variants rs35934224 in TXNRD2 and rs6478746 in LMX1B in primary angle-closure and pseudoexfoliation glaucoma.PMID 34461764Read ↗

Association of variants in the ATXN2 (rs7137828), FOXC1 (rs2745572) and TXNRD2 (rs35934224) genes as risk factors for primary open-angle glaucoma development in a Brazilian cohort.Semantic proximity Read ↗

Polymorphism rs3742330 in microRNA Biogenesis Gene DICER1 Is Associated with Pseudoexfoliation Glaucoma in Saudi Cohort.Semantic proximity Read ↗

Genetic Associations of Primary Angle-Closure Disease: A Systematic Review and Meta-analysis.Semantic proximity Read ↗

Association analysis of polymorphisms rs12997 in ACVR1 and rs1043784 in BMP6 genes involved in bone morphogenic protein signaling pathway in primary angle-closure and pseudoexfoliation glaucoma patients of Saudi origin.Semantic proximity Read ↗

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma.Semantic proximity Read ↗

Primary angle closure glaucoma genomic associations and disease mechanismSemantic proximity Read ↗

Genetic Association of Primary Angle-Closure Glaucoma and Disease Progression.Semantic proximity Read ↗

Analysis of LOXL1 polymorphisms in a Saudi Arabian population with pseudoexfoliation glaucoma.Semantic proximity Read ↗

Lack of association between LOXL1 gene polymorphisms and primary open angle glaucoma in the Saudi Arabian population.Semantic proximity Read ↗

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populationsSemantic proximity Read ↗

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.Semantic proximity Read ↗

Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.