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Article

Additive effects of genetic variants associated with intraocular pressure in primary open-angle glaucoma.

PloS one - 1 Jan 2017

Mabuchi Fumihiko, Mabuchi Nakako, Sakurada Yoichi, Yoneyama Seigo, Kashiwagi Kenji, Iijima Hiroyuki, Yamagata Zentaro, Takamoto Mitsuko, Aihara Makoto, Iwata Takeshi, Kawase Kazuhide, Shiga Yukihiro, Nishiguchi Koji M, Nakazawa Toru, Ozaki Mineo, Araie Makoto

Abstract excerpt

To investigate the association between the additive effects of genetic variants associated with intraocular pressure (IOP) and IOP, vertical cup-to-disc ratio (VCDR), and high tension glaucoma (HTG) or normal tension glaucoma (NTG) as phenotypic features of primary open-angle glaucoma (POAG), and to evaluate the clinical usefulness of the additive effects of IOP-related genetic variants for predicting IOP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28832686
DOI: 10.1371/journal.pone.0183709
PMCID: PMC5568337

Genes

ABCA1
ABO
AGBL2
ARHGEF12
CAV2
GAS7
GLCCI1
ICA1
PTPRJ

Provenance

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