Article
Can polymorphisms in the fatty acid desaturase (FADS) gene cluster alter the effects of fish oil supplementation on plasma and erythrocyte fatty acid profiles? An exploratory study.
European journal of nutrition - 1 Oct 2018
Meldrum Suzanne J, Li Yuchun, Zhang Guicheng, Heaton Alexandra E M, D'Vaz Nina, Manz Judith, Reischl Eva, Koletzko Berthold V, Prescott Susan L, Simmer Karen
Abstract excerpt
PURPOSE: The enzymes encoded by fatty acid desaturases (FADS) genes determine the desaturation of long-chain polyunsaturated fatty acids (LCPUFA). We investigated if haplotype and single nucleotide polymorphisms (SNPs) in FADS gene cluster can influence LCPUFA status in infants who received either fish oil or placebo supplementation. METHODS: Children enrolled in the Infant Fish Oil Supplementation Study (IFOS)...
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