Article
Maternal and child fatty acid desaturase genotype as determinants of cord blood long-chain PUFA (LCPUFA) concentrations in the Seychelles Child Development Study.
The British journal of nutrition - 14 Dec 2021
Conway Marie C, McSorley Emeir M, Mulhern Maria S, Spence Toni, Weslowska Maria, Strain J J, van Wijngaarden Edwin, Davidson Phil W, Myers Gary J, Wahlberg Karin E, Shamlaye Conrad F, Cobice Diego F, Hyland Barry W, Pineda Daniela, Broberg Karin, Yeates Alison J
Abstract excerpt
Optimal maternal long-chain PUFA (LCPUFA) status is essential for the developing fetus. The fatty acid desaturase (FADS) genes are involved in the endogenous synthesis of LCPUFA. The minor allele of various FADS SNP have been associated with increased maternal concentrations of the precursors linoleic acid (LA) and α-linolenic acid (ALA), and lower concentrations of arachidonic acid (AA) and DHA. There is limited...
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