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Article

Population genomics of virulence genes of Plasmodium falciparum in clinical isolates from Uganda.

Scientific reports - 18 Sept 2017

Ruybal-Pesántez Shazia, Tiedje Kathryn E, Tonkin-Hill Gerry, Rask Thomas S, Kamya Moses R, Greenhouse Bryan, Dorsey Grant, Duffy Michael F, Day Karen P

Abstract excerpt

Plasmodium falciparum causes a spectrum of malarial disease from asymptomatic to uncomplicated through to severe. Investigations of parasite virulence have associated the expression of distinct variants of the major surface antigen of the blood stages known as Pf EMP1 encoded by up to 60 var genes per genome. Looking at the population genomics of var genes in cases of uncomplicated malaria, we set out to...

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Identifiers

PMID: 28924231
DOI: 10.1038/s41598-017-11814-9
PMCID: PMC5603532

Genes

EMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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